In a groundbreaking development for addressing future viral pandemics, a multi-institutional team involving Lawrence Livermore National Laboratory (LLNL) researchers has successfully combined an artificial intelligence (AI)-backed platform with supercomputing to redesign and restore the effectiveness of antibodies whose ability to fight viruses has been compromised by viral evolution.
The team’s research is published in the journal Nature and showcases a novel antibody design platform comprising experimental data, structural biology, bioinformatic modeling and molecular simulations — driven by a machine-learning algorithm.
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