LLNL and BridgeBio announce trials for supercomputing-discovered cancer drug

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In a milestone for supercomputing-aided drug design, Lawrence Livermore National Laboratory and BridgeBio Oncology Therapeutics today announced clinical trials have begun for a first-in-class medication that targets specific genetic mutations implicated in many types of cancer. The drug discovery work was powered by LLNL supercomputers Ruby (shown), Quartz and Lassen. Graphic by Amanda Levasseur.

In a substantial milestone for supercomputing-aided drug design, Lawrence Livermore National Laboratory (LLNL) and BridgeBio Oncology Therapeutics (BridgeBio) today announced clinical trials have begun for a first-in-class medication that targets specific genetic mutations implicated in many types of cancer.

LLNL Innovation and Partnerships Office (IPO) Business Development Executive Yash Vaishnav negotiated the CRADA with BridgeBio subsidiary Theras, as well as the license agreement for the drug candidate with BridgeBio Oncology Therapeutics. Vaishnav also manages the intellectual property portfolio of KRAS inhibitors developed under the CRADA and the relationship with his counterparts at BridgeBio.