Life Sciences, Biotech, and Healthcare

LLNL inventors developed a proprietary desorption technology that enabled separation of a near-adjacent panel of REEs, marking the best separation...

Genetic engineering allows insertion and propagation of a foreign genetic element in a heterologous system in a variety of applications such as the...

LLNL researchers have developed an approach to form silicon carbide (and diamond) nanoneedles using plasma etching that create micro pillars followed...

After screening at least 50 different cyclodextrins, LLNL researchers found that the drug Subetadex shows enhanced affinities for fentanyl and its...

Rather than using genes carried by viruses, LLNL researchers have developed an alternative approach of delivering CAR to T-cells in form of proteins...

LLNL inventors have developed a method and device for the high throughput screening of various chemical and biological entities using a novel...

LLNL inventors have developed a proprietary concept and a prototype NVU device that provides an effective in vitro model of the BBB to discover...

LLNL researchers have designed and developed a novel high-density, high-channel count 3D connector that enables hundreds or thousands of nonpermanent...

As an important step toward overcoming the technical and environmental limitations of current REE processing methods, the LLNL team has patented and...

LLNL researchers have enhanced and expanded the IDEA technology, which fabricates micron-scale droplets that are then crosslinked in-air (within...

LLNL researchers have discovered that some inexpensive and commercially available molecules used for other applications, could render certain...

To address shortcomings of current liposome drug delivery systems, the patented innovation uses drug-loaded liposomes containing carbon nanotube...

A new approach of developing synthetic antibacterial mineral assemblages can be used as an alternative treatment when traditional antibiotics fail in...

The method described in a pending patent application uses a novel thiacrown (dibenzohexathia-18-crown-6) for efficient extraction of 197m,gHg and...

Combining the principles of nanotechnology, cell-free protein synthesis and microfluidics, LLNL researchers have developed a reusable, portable...

Many of the disadvantages of current interface devices can be overcome with LLNL’s novel interface design, which relies on area array distribution...

To replicate the physiology and functionality of tissues and organs, LLNL has developed an in vitro device that contains 3D MEAs made from flexible...

LLNL’s high throughput method involves proteome-wide screening for linear B-cell epitopes using native proteomes isolated from a pathogen of interest...

Commercial fiber optic cables are the current standard for carrying optical signals in industries like communications or medical devices. However, the...

Solid-state distributed node-based rapid thermal cycler for extremely fast nucleic acid amplification (LLNL Internal Case # IL-12275, US Patent 8,720...

Laser heating of aqueous samples on a micro-optical-electro-mechanical system (LLNL Internal Case # IL-11719, US Patents 8,367,976 ; 8,610,032 )...

LLNL researchers have designed a synthetic, concatemeric bacterial expression vector that expresses a protein sequence that can be digested into a...

LLNL scientists have created a technology that utilizes electrical means, instead of optical methods, to (1) provide label-free detection of droplet...

This device allows for observation of single cells encapsulated in droplets and provide the ability to recover droplets containing a cell of interest...

This invention consists of a functionalized membrane (e.g. polyethylene glycol (PEG)) and osmosis or electric potential as a driving force. The PEG...

This invention is an improved chromatography device that utilizes the concept of a functionally graded material (FGM) for separation of components...

The art described here incorporates a planar integrated optical system that allows for multiple biochemical assays to be run at the same time or...

This technology describes a method for partitioning fluid into “packets” between polymeric sheets. The fluid to be partitioned is introduced between...

LLNL researchers have developed a variation of AMS technology that improves sample preparation, analysis, and cost for AMS. The device involves...

LLNL has invented a new high-throughput assay for sample separation that uses the vibrations of a piezoelectric transducer to produce acoustic...

LLNL researchers have developed an apparatus capable of measuring and recording ultraviolet radiation that uses the Schottky diode/ZnSe/metal type UV...

The invention developed by LLNL researchers proposes to use staged isotachophoresis to improve sample separation. One of the problems with...

LLNL researchers have devolved a technique to separate or purify samples using electrophoretic separation. This invention corrects the problem...

Researchers at LLNL have developed a more efficient and cost-effective method and system for synthesizing a critical D-aminoluciferin precursor and...

LLNL's technology employs improved sorting strategies related to chip-based droplet sorting. This technology uses electromagnetic fields and non...

Researchers at LLNL have developed a method to passively sort individual microdroplet samples of uniform size based on stiffness and viscosity. Unlike...

LLNL researchers have created a method that uses isotachophoresis for the exclusion and or purification of nucleic acids. Isotachopheresis (ITP) is an...

The steady-state phenomenon generates thousands of microdroplets per second which is a problem when the stream of droplets needs to be slowed down or...

The present invention uses magnetic fields to hold particles in place for faster DNA amplification and sequencing. This invention provides a method...

This invention is designed to sort and identify complex samples using parallel nucleic acid characterization. By isolating single or double stranded...

This technology is a photonic detection system developed by researchers at LLNL for the detection of biological or chemical threats with the intention...

The described invention is a miniature fluidic device for separating particles suspended within a liquid sample that is introduced into the interior...

Researchers at LLNL have developed a nanotube sensor (single-walled or multi-walled carbon nanotubes) enclosed within a highly selective lipid bilayer...

Researchers at LLNL have created a new technology for performing pumping and valving operations in microfabricated fluidic systems. Traditional...

Researchers at LLNL have developed a new method to utilize highly selective molecular recognition events to attach proteins to any solid support...

LLNL has a successful history of developing instruments for detecting and characterizing airborne pathogens. Often, aerosol characterizing instruments...

LLNL scientists have designed a rapid PCR technology that incorporates the use of microfluidic thermal heat exchanger systems and is comprised of a...

LLNL has developed a new technology that provides a method for near-instantaneous heating of aqueous samples in microfluidic devices. The technology...

Researchers at LLNL have developed an instantaneous sample heating method to efficiently deposit thermal energy into a continuous stream or segmented...

Researchers at LLNL have designed a new technology that allows the integration of a large bench-top thermal cycling instrument onto a miniaturized...

LLNL researchers have developed a high-volume, low-cost diagnostic test that is easy to use and provides results in under an hour. The testing...

This technology describes a method for performing immediate in-line sample heating to promote the required chemical reactions for amplification...

LLNL researchers have developed a new method for faster, more accurate, and precise thermal control for DNA amplification. This technology uses sensor...

LLNL scientists developed novel hydrogels, which are biodegradable soft materials synthesized by a water-soluble polymer. Incorporating silver imparts...

LLNL researchers have developed a method to quickly and accurately identify the family of a virus infecting a vertebrate via PCR. Universal primer...

LLNL scientists have developed a high-confidence, real-time multiplexed reverse transcriptase PCR (RT-PCR) rule-out assay for foot and mouth disease...

LLNL scientists have developed a method to ensure the accuracy of that tomographic image by applying adaptive optics (AO) to OCT in a single...

LLNL researchers have developed a portable device which analyzes one or multiple types of body fluids or gases to test for one or more medical...

LLNL researchers have invented a system for identifying all known and unknown pathogenic or non-pathogenic organisms in a sample. This invention takes...

This LLNL-developed invention is multiplexed and utilizes the Luminex bead-based liquid array, which contains 100 different unique beads...

LNLL scientists have invented a method for multiplexed detection of PCR amplified products which can be completed in a single step. Highly validated...

LLNL scientists have developed a battery-powered device which is low-cost and multi-chambered for the extraction and amplification of nucleic acids...

LLNL has developed a brain-on-a-chip system with a removable cell-seeding funnel to simultaneously localize neurons from various brain regions in an...

Lawrence Livermore National Laboratory scientists have developed a signal enhancing microchip apparatus and method that enhances a microfluidic...

Using various excitation wavelengths, a hyperspectral microscope takes advantage of autofluorescence and polarized light scattering from cellular...

LLNL has developed a novel process of production, isolation, characterization, and functional re-constitution of membrane-associated proteins in a...

LLNL’s BioBriefcase is a compact and portable instrument capable of autonomously detecting the full spectrum of bioagents, including bacteria, viruses...

The biotech industry aims to move towards an on-chip system for sample generation, amplification and detection of both DNA and RNA based organisms...

LLNL has developed a technology that provides near-instantaneous heating of aqueous samples in microfluidic devices. The method heats samples in a...

This technology uses either of two X-ray wave-front sensor techniques, Hartmann sensing and two-dimensional shear interferometry, both of which are...