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Technology Portfolios

3D MEA device prior to actuation. A) A completed device. B) Close-up image of a single cell culture well. The large dark metal features at the top and bottom of each cell culture well are ground electrodes, which are all electrically shorted to each other. C) Light micrograph of a single 3DMEA post-actuation. The hinge regions are plastically deformed and allow the probes to stand upright without additional supports.
A 3-dimensional in vitro flexible microelectrode array (MEA)

To replicate the physiology and functionality of tissues and organs, LLNL has developed an in vitro device that contains 3D MEAs made from flexible polymeric probes with multiple electrodes along the body of each probe. At the end of each probe body is a specially designed hinge that allows the probe to transition from lying flat to a more upright position when actuated and then…

Computer designed bridge
Development of an Application Programming Interface (API) to merge Computer Aided Design (CAD) software and Livermore Design Optimization (LiDO) code

The LiDO code combines finite element analysis, design sensitivity analysis and nonlinear programming in a High-Performance Computing (HPC) environment that enables the solution of large-scale structural optimization problems in a computationally efficient manner. Currently, the code uses topology optimization strategies in which a given material is optimally distributed throughout the domain…