CANDLE is an artificial intelligence-based computer code that brings together machine learning, deep learning and cancer research to accelerate the discovery of new cancer therapies and treatments. 

Pushing supercomputers to their limits requires a deeper understanding of power and energy than standard software and operating systems allow. Variorum provides robust interfaces that measure and optimize computation at the physical level: temperature, cycles, energy, and power. With Variorum, administrators and users can efficiently and effectively use computing resources.

Learn more: https://computing.llnl.gov/projects/variorum

The zfp software library provides a comprehensive solution to both lossy and lossless data compression. zfp reduces the storage space of high-precision floating-point data without sacrificing accuracy. It was designed to be a compact number format for storing data arrays in-memory in compressed form while supporting high-speed random access.

Learn more: https://computing.llnl.gov/projects/zfp

HELD Gratings, a novel design of multi-layer dielectric pulse compression gratings, enables a new class of high-energy, 10 PW ultrafast laser systems for extremely high and unprecedented peak power. Meter-scale HELD Gratings have the potential to facilitate future 100 PW-class ultrafast laser systems.

Energy Inks meet 3D printing material flow conditions while optimizing functional properties of the extruded material, requirements difficult to obtain simultaneously. Such functional inks enable the design of customizable, easily integrated components, and, therefore, next-generation high-performance energy devices including those not possible to produce using current methods.

Tailored Glass by DIW augments Direct Ink Writing additive manufacturing to print silica-based optics and glass components with customizable forms and spatially varying material properties. Flow of multiple glass-forming inks is finely controlled to achieve the desired structure and optical properties. Subsequent heat treatment renders a dense, transparent glass product.

Flux is a next-generation workload management software framework for high-performance computing (HPC). It combines fully hierarchical resource management with graph-based scheduling to improve the performance, portability, flexibility, and manageability of scheduling and execution of complex scientific workflows on HPC systems both at the system and user level.
 

The Multiplicity Counter for Thermal and Fast Neutrons (MC-TF) is a field-deployable device that first responders can use to quickly assess in real-time and with high confidence the threat level posed by a suspected nuclear weapon. The MC-TF is designed to detect time-correlated fast and thermal neutrons unique to special nuclear material (SNM); the core of a nuclear weapon.

The Optical Transconductance Varistor (OTV) is a light-triggered semiconductor power switch enabling higher switching speeds than competitors at previously unattainable voltages to facilitate more efficient grid-scale power conversion, reduce expensive, environmentally-damaging energy losses, and generate the voltages required for medical proton therapy or air disinfection.