Accelerator mass spectrometry (AMS) is a powerful bioanalytical method that allows for the analysis of specific elements in a sample. AMS technologies are broadly used in the biomedical, toxicology and pharmacology field. It can be used for the labeling of drugs for drug tracing studies, bone mass measurements, the assessment of environmental toxicants, and for drug-target binding as a biomarker of response to chemotherapy. The technology works by converting the atoms in the sample into a beam of fast-moving ions which will then be measured by a magnetic or electric field. AMS technologies require a minimum sample size (less than 1 mg) of carbon and proper isotope dilution which can be a tedious and long process. Accurate analysis with AMS also depends on careful sample “accounting”: homogenization, control of any volatile components, and quantitation of amounts of carrier compounds. In addition, sample preparation and analysis by AMS can be very expensive. The technology described here reduces, from days to minutes, the time required for biochemical samples preparation and analysis by AMS. The technology also decreases the costs of sample preparation and analysis.