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SEM image of a prototype for a neural implant shuttle etched into a non-SOI wafer. The 7:1 (Si:Photoresist) etch selectivity used here allowed for a maximum structure height of 32 μm, with up to 75 steps of 0.4 μm height each. Scale bar 100 μm.

For this method, a Silicon on Insulator (SOI) wafer is used to tailor etch rates and thickness in initial steps of the process.  The simple three step process approach is comprised of grayscale lithography, deep reactive-ion etch (DRIE) and liftoff of the SOI wafer.  The liftoff process is used to dissolve the insulating layer, thus separating sections of the wafer as individual silicon…

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Livermore researchers have developed a method for implementing closed-loop control in extrusion printing processes by means of novel sensing, machine learning, and optimal control algorithms for the optimization of printing parameters and controllability. The system includes a suite of sensors, including cameras, voltage and current meters, scales, etc., that provide in-situ process monitoring…
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mesoscale_nand_gate

Recent advancements in additive manufacturing, also called 3D printing, allow precise placement of materials in three dimensions. LLNL researchers have invented mechanical logic gates based on flexures that can be integrated into the microstructure of a micro-architected material through 3D printing. The logic gates can be combined into circuits allowing complex logic operations to be…

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Optics

The LLNL method for optimizing as built optical designs uses insights from perturbed optical system theory and reformulates perturbation of optical performance in terms of double Zernikes, which can be calculated analytically rather than by tracing thousands of rays. A new theory of compensation is enabled by the use of double Zernikes which allows the performance degradation of a perturbed…

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Machine Learning for Monitoring microfluidic microcapsules
LLNL researchers have developed a system that relies on machine learning to monitor microfluidic devices. The system includes (at least) a microfluidic device, sensor(s), and a local network computer. The system could also include a camera that takes real-time images of channel(s) within an operating microfluidic device. A subset of these images can be used to train/teach a machine learning…
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microcantilever3

LLNL has developed a compact and low-power cantilever-based sensor array, which has been used to detect various vapor-phase analytes. For further information on the latest developments, see the article "Sniffing the Air with an Electronic Nose."