LLNL’s high throughput method involves proteome-wide screening for linear B-cell epitopes using native proteomes isolated from a pathogen of interest and convalescent sera from immunized animals. LLNL researchers have applied their newly developed generalizable screening method to the identification of pathogenic bacteria by screening linear B-cell epitopes in the proteome of Francisella…

LLNL uses the additive manufacturing technique known as Electrophoretic Deposition to shape the source particle material into a finished magnet geometry. The source particle material is dispersed in a liquid so that the particles can move freely. Electric fields in the shape of the finished product then draw the particles to the desired location to form a “green body”, much like an unfired…

LLNL has developed a novel process of production, isolation, characterization, and functional re-constitution of membrane-associated proteins in a single step. In addition, LLNL has developed a colorimetric assay that indicates production, correct folding, and incorporation of bR into soluble nanolipoprotein particles (NLPs).

LLNL has developed an approach, for formation of NLP/…