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Cross Section of the High-Voltage Insulator Joint

The approach is to build a high voltage insulator consisting of two materials:  Poly-Ether-Ether-Ketone (“PEEK”) and Machinable Ceramic (“MACOR”).  PEEK has a high stress tolerance but cannot withstand high temperatures, while MACOR has high heat tolerance but is difficult to machine and can be brittle.  MACOR is used for the plasma-facing surface, while PEEK will handle the stresses and high…

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An artist’s concept rendering of a 3.5-meter linear induction accelerator (LIA) with four lines-of-sight toward a patient. The blue elements magnetically focus and direct the LIA’s electron beams.

LLNL’s approach is to use their patented Photoconductive Charge Trapping Apparatus (U.S. Patent No. 11,366,401) as the active switch needed to discharge voltage across a vacuum gap in a particle accelerator, like the one described in their other patent (U.S. Patent No.

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Immunoproteomic workflow to identify antigenic peptides.

LLNL’s high throughput method involves proteome-wide screening for linear B-cell epitopes using native proteomes isolated from a pathogen of interest and convalescent sera from immunized animals. LLNL researchers have applied their newly developed generalizable screening method to the identification of pathogenic bacteria by screening linear B-cell epitopes in the proteome of Francisella…

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nanolipoprotein particles

LLNL has developed a novel process of production, isolation, characterization, and functional re-constitution of membrane-associated proteins in a single step. In addition, LLNL has developed a colorimetric assay that indicates production, correct folding, and incorporation of bR into soluble nanolipoprotein particles (NLPs).

LLNL has developed an approach, for formation of NLP/…