LLNL’s high throughput method involves proteome-wide screening for linear B-cell epitopes using native proteomes isolated from a pathogen of interest and convalescent sera from immunized animals.
Keywords
- Show all (103)
- Instrumentation (39)
- Diagnostics (12)
- Electric Grid (7)
- Therapeutics (7)
- Carbon Utilization (6)
- Brain Computer Interface (BCI) (4)
- Materials for Energy Products (4)
- Additive Manufacturing (3)
- Direct Air Capture (3)
- Synthesis and Processing (3)
- 3D Printing (2)
- Inertial Fusion Energy (IFE) (2)
- Power Electronics (2)
- Rare Earth Elements (REEs) (2)
- Geologic Storage (1)
- Inertial Confinement Fusion (ICF) (1)
- Membranes (1)
- Semiconductors (1)
- Simulation (1)
- (-) Vaccines (2)
Technology Portfolios
Image

High throughput discovery of linear B-cell epitopes for the development of vaccines and therapeutics
Image

LLNL has developed a novel process of production, isolation, characterization, and functional re-constitution of membrane-associated proteins in a single step. In addition, LLNL has developed a colorimetric assay that indicates production, correct folding, and incorporation of bR into soluble nanolipoprotein particles (NLPs).
LLNL has developed an approach, for formation of NLP/…