To address shortcomings of current liposome drug delivery systems, the patented innovation uses drug-loaded liposomes containing carbon nanotube porins (CNTPs) inserted into the liposomal membranes for the delivery of the encapsulated drugs. Short CNTPs (10 nm in length) with narrow diameter (0.8 nm) has been demonstrated to facilitate efficient fusion of lipid bilayers resulting in the…
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![SEM image of iron-sulfide spheres](/sites/default/files/styles/scale_exact_400x400_/public/2023-05/iron-sulfide%20spheres.jpg?itok=X03OXhag)
A new approach of developing synthetic antibacterial mineral assemblages can be used as an alternative treatment when traditional antibiotics fail in clinical and agricultural settings. Mineral mixtures can be synthesized with tunable metal release and reactive oxygen species generation that are capable of killing human pathogens and promoting wound healing. One of the key components in the…
![novel thiacrown ethers for isolating of 197gHg and 197m,gHg](/sites/default/files/styles/scale_exact_400x400_/public/2023-05/novel%20thiacrown%20ether.png?itok=afjvUtSX)
The method described in a pending patent application uses a novel thiacrown (dibenzohexathia-18-crown-6) for efficient extraction of 197m,gHg and 197gHg from irradiated Pt target foils. The separation of 197m,gHg and 197gHg from Pt foils using this novel thiacrown was found to be highly specific. No detectable amount of the Pt foil was seen in the…
![High Density Protein Translation System: Nanotubes used to greatly increase the density of ribosomes on a surface by adding a third dimension (height) to enable multiple ribosomal attachment sites.](/sites/default/files/styles/scale_exact_400x400_/public/2023-04/High%20Density%20Protein%20Translation%20System.png?itok=zerUPjta)
Combining the principles of nanotechnology, cell-free protein synthesis and microfluidics, LLNL researchers have developed a reusable, portable programmable system that can create purified, concentrated protein product in vitro in a microfluidic device containing nucleic acids.
![AI Innovation Incubator](/sites/default/files/styles/scale_exact_400x400_/public/2022-01/AI%20Innovation%20Incubator.jpg?itok=B8jcKPOy)
Lawrence Livermore National Laboratory (LLNL) is offering the opportunity to collaborate in accelerating artificial intelligence (AI) for applied science, including research in key areas such as advanced material design, 3D printing, predictive biology, energy systems, “self-driving” lasers and fusion energy research.
![Catalyst HPC cluster](/sites/default/files/styles/scale_exact_400x400_/public/2022-06/Catalyst%20HPC%20cluster.jpg?itok=k9uYS5xL)
Clinical images have a wealth of data that are currently untapped by physicians and machine learning (ML) methods alike. Most ML methods require more data than is available to sufficiently train them. In order to obtain all data contained in a clinical image, it is imperative to be able to utilize multimodal, or various types of, data such as tags or identifications, especially where spatial…
![medical_x-rays_x-ray_tech](/sites/default/files/styles/scale_exact_400x400_/public/2022-06/medical_x-rays_x-ray_tech_1.jpg?itok=kn0J-DkH)
Some COVID-19 diagnoses are utilizing computed tomography (CT)-scans for triage. CT-scans produce immediate results with high sensitivity. The digital images produced by a CT-scan require physicians to identify objects within the image to determine the presence of disease. Object identification can be done using machine learning (ML) techniques such as deep learning (DL) to improve speed and…
![MimicGAN data set example](/sites/default/files/styles/scale_exact_400x400_/public/2020-05/mimicgan_robustness_to_rotation.png?itok=yacM18ra)
MimicGAN represents a new generation of methods that can “self-correct” for unseen corruptions in the data out in the field. This is particularly useful for systems that need to be deployed autonomously without needing constant intervention such as Automated Driver Assistance Systems. MimicGAN achieves this by treating every test sample as “corrupt” by default. The goal is to determine (a) the…
![blue bacteria](/sites/default/files/styles/scale_exact_400x400_/public/2022-07/blue%20bacteria.jpg?itok=ddcclBXg)
LLNL scientists developed novel hydrogels, which are biodegradable soft materials synthesized by a water-soluble polymer. Incorporating silver imparts antimicrobial activity to the material at low concentration compared to currently used silver nanoparticles. Our hydrogels are composed of silver ions instead of silver nanoparticles, which eliminates the toxicity concerns of modern silver…
![drift_meter_thumb.jpg drift_meter_thumb](/sites/default/files/styles/scale_exact_400x400_/public/2019-08/drift_meter_thumb.jpg?itok=1NiNsyHm)
LLNL’s Optically-based Interstory Drift Meter System provides a means to accurately measure the dynamic interstory drift of a vibrating building (or other structure) during earthquake shaking. This technology addresses many of the shortcomings associated with traditional strong motion accelerometer based building monitoring.
LLNL’s discrete diode position sensitive device is a newly…
![medical_x-rays_x-ray_tech](/sites/default/files/styles/scale_exact_400x400_/public/2022-06/medical_x-rays_x-ray_tech_1.jpg?itok=kn0J-DkH)
LLNL has developed a new system, called the Segmentation Ensembles System, that provides a simple and general way to fuse high-level and low-level information and leads to a substantial increase in overall performance of digital image analysis. LLNL researchers have demonstrated the effectiveness of the approach on applications ranging from automatic threat detection for airport security, to…
![Electronic Wave](/sites/default/files/styles/scale_exact_400x400_/public/2022-06/electronic%20wave.jpg?itok=v7aKMJKH)
The invention relates to a measurement method and system for capturing both the amplitude and phase temporal profile of a transient waveform or a selected number of consecutive waveforms having bandwidths of up to about 10 THz in a single shot or in a high repetition rate mode. The invention consists of an optical preprocessor which can then output a time-scaled replica of the input signal to…