LLNL researchers have developed a method to enhance the performance of polyelectrolyte membranes by using a humidity-controlled crosslinking process which can be applied to precisely adjust the water channels of the membrane.
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![3D MEA device prior to actuation. A) A completed device. B) Close-up image of a single cell culture well. The large dark metal features at the top and bottom of each cell culture well are ground electrodes, which are all electrically shorted to each other. C) Light micrograph of a single 3DMEA post-actuation. The hinge regions are plastically deformed and allow the probes to stand upright without additional supports.](/sites/default/files/styles/scale_exact_400x400_/public/2023-04/3D_MEA_device.png?itok=5ltXynKC)
To replicate the physiology and functionality of tissues and organs, LLNL has developed an in vitro device that contains 3D MEAs made from flexible polymeric probes with multiple electrodes along the body of each probe. At the end of each probe body is a specially designed hinge that allows the probe to transition from lying flat to a more upright position when actuated and then…
![Plasma wind](/sites/default/files/styles/scale_exact_400x400_/public/2022-08/Plasma%20wind%20.png?itok=RB5iLhMv)
![Intrinsic Use Control](/sites/default/files/styles/scale_exact_400x400_/public/2022-06/Intrinsic%20Use%20Control.jpg?itok=plVEiBwC)
LLNL's method of equivalent time sampling incorporates an embedded system that generates the pulses used to trigger the external circuit and the data acquisition (DAQ). This removes the external reference clock, allowing the overall system clock rate to change based on the ability of the embedded system. The time delays needed to create the time stepping for equivalent time sampling is done by…