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A typical first responder training visualization that employs simulated gamma-ray and neutron radiation interactions within a virtual scenario. (Images by Ryan Chen.)

To address the need for realistic and high-fidelity first responder training, a multidisciplinary team at LLNL has worked to establish the new gold standard simulator called TARANTULA (Tactical Augmented Reality Applications for Nuclear Emergency Support Team (NEST) Training using Livermore Analytics). TARANTULA is a scientifically accurate, fully functional, field-deployable simulator that…

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The image is a montage of an artist’s depiction of a liposomal drug carrier studded with carbon nanotube porins that is docking to a cancer cell surface and delivering chemotherapy cargo with a fluorescence microscopy image of stained cells exposed to these carriers. The red stain indicates that the cells are dead and the treatment was successful. Images by P. Lastrico of MPI and N.T. Ho and A. Noy of LLNL.

To address shortcomings of current liposome drug delivery systems, the patented innovation uses drug-loaded liposomes containing carbon nanotube porins (CNTPs) inserted into the liposomal membranes for the delivery of the encapsulated drugs. Short CNTPs (10 nm in length) with narrow diameter (0.8 nm) has been demonstrated to facilitate efficient fusion of lipid bilayers resulting in the…

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SEM image of iron-sulfide spheres

A new approach of developing synthetic antibacterial mineral assemblages can be used as an alternative treatment when traditional antibiotics fail in clinical and agricultural settings. Mineral mixtures can be synthesized with tunable metal release and reactive oxygen species generation that are capable of killing human pathogens and promoting wound healing. One of the key components in the…

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novel thiacrown ethers for isolating of 197gHg and 197m,gHg

The method described in a pending patent application uses a novel thiacrown (dibenzohexathia-18-crown-6) for efficient extraction of 197m,gHg and 197gHg from irradiated Pt target foils. The separation of 197m,gHg and 197gHg from Pt foils using this novel thiacrown was found to be highly specific. No detectable amount of the Pt foil was seen in the…

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High Density Protein Translation System: Nanotubes used to greatly increase the density of ribosomes on a surface by adding a third dimension (height) to enable multiple ribosomal attachment sites.

Combining the principles of nanotechnology, cell-free protein synthesis and microfluidics, LLNL researchers have developed a reusable, portable programmable system that can create purified, concentrated protein product in vitro in a microfluidic device containing nucleic acids.

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blue bacteria

LLNL scientists developed novel hydrogels, which are biodegradable soft materials synthesized by a water-soluble polymer. Incorporating silver imparts antimicrobial activity to the material at low concentration compared to currently used silver nanoparticles. Our hydrogels are composed of silver ions instead of silver nanoparticles, which eliminates the toxicity concerns of modern silver…

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Radiation Training Field Simulator (RaFTS).

There are three main components to the RaFTS system: 1) the radiation detector, which can be of any type and from any manufacturer; 2) the RaFTS electronics, which produce the electronic pulses that are injected into the electronics of the radiation detector through a (to be) standardized port interface; and 3) the exercise scenario, which defines the synthetic radiation field and time-varying…