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A digital twin (right) is the virtual representation of real-world objects and processes (left)
Digital Twin of Structured Light Metrology

LLNL’s novel approach utilizes a number of techniques to improve reconstruction accuracy:

  • Better coding scheme-based techniques
  • Hardware-assisted techniques
  • Adaptive fringe projection techniques
  • Multi-exposure based techniques

The method requires specific calibration procedures and control of the hardware, which is achieved through a digital twin…

Immunoproteomic workflow to identify antigenic peptides.
High throughput discovery of linear B-cell epitopes for the development of vaccines and therapeutics

LLNL’s high throughput method involves proteome-wide screening for linear B-cell epitopes using native proteomes isolated from a pathogen of interest and convalescent sera from immunized animals.

A cold-spray chamber is shown during deposition, with the nozzle at the top of the image and a near-full density sample being fabricated in the center. Particles of the brittle thermoelectric bismuth telluride are accelerated to more than 900 meters per second, or almost Mach 3, in inert gas and directed onto a copper surface, laying down the strips that form the basis of a functioning thermoelectric generator to harvest waste heat. Graphic by Jacob Long/LLNL
Versatile Cold Spray
Versatile Cold Spray (VCS) enables deposition of brittle materials, such as thermoelectrics, magnets, and insulators, while retaining their functional properties. Materials can be deposited on substrates or arbitrary shapes with no requirement to match compositions. The VCS system is low cost, easily portable, and easy to use. VCS has been developed in a collaboration between Lawrence Livermore…
nanolipoprotein particles
Cell-Free Assembly of NanoLipoprotein Particles

LLNL has developed a novel process of production, isolation, characterization, and functional re-constitution of membrane-associated proteins in a single step. In addition, LLNL has developed a colorimetric assay that indicates production, correct folding, and incorporation of bR into soluble nanolipoprotein particles (NLPs).

LLNL has developed an approach, for formation of NLP/…